Basic Info
Product name:Diphenhydramine hydrochloride Appearance: White Powder CAS: 147-24-0
MF: C17H22ClNO
EINECS No:205-687-2
Molecular weithgs:291.82 Melting point:168-172°C
Purity:99%
Shelf life:2 years Storage:Keep in cool dry place. | Physical&Chemical Control | ||
| ITEM | SPECIFICATION | RESULTS |
| Appearance | Fine powder | Complies |
| Color | white | Complies |
| Odor&Taste | Characteristic | Complies |
| Assay | ≥99% | 99.53% |
| Heavy Metals | ≤10ppm | Complies |
| Pb | ≤2ppm | Complies |
| As | ≤2ppm | Complies |
| Hg | ≤1ppm | Complies |
| Cadmium | ≤1ppm | Complies |
| Sulphates | ≤300ppm | Complies |
| Ammonium | ≤200ppm | Complies |
| Iron | ≤10ppm | Complies |
| Microbiological Control | ||
| Total plate count | ≤1000CFU/G | Complies |
| Yeast & mold | ≤100 CFU /G | Complies |
| Total coli forms | ≤100 CFU /G | Complies |
| E.coli | Negative | Negative |
| Salmonella | Negative | Negative |
Product description:Diphenhydramine HCl (Benadryl), a histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations.Target: Histamine H1 receptorDiphenhydramine HCl (Benadryl), a histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects. Diphenhydramine competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. Function & Application:enhydramine hydrochloride can eliminate all kinds of allergic symptoms, among which the pivotal inhibitory effect is remarkable;still has the sedative, the anti- halo movement and the antiemetic effect, also has the anti-choline effect, may alleviate the bronchial smooth muscle spasm. Also has the local anesthesia function, may local application treats the skin pruritus. can be used for hay fever, urticaria, etc.
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